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Updated: Jul 23, 2026
11:11
Isolation and Expansion of Cytotoxic Cytokine-induced Killer T Cells for Cancer Treatment
Published on: January 24, 2020
Cytokines and advanced cancer
1St. Christopher's Hospice, Esher, Surrey, United Kingdom.
Journal of Pain and Symptom Management
|October 6, 2000
Summary
Cytokines, signaling proteins, are implicated in cancer progression and symptoms like pain and fatigue. New anti-cytokine therapies may offer better symptom control for advanced cancer patients.
Area of Science:
- Oncology
- Immunology
- Cancer Biology
Background:
- Cytokines play a crucial role in cancer development and metastasis.
- Elevated cytokine levels are frequently observed in individuals with cancer.
- Cytokines are linked to numerous symptoms in advanced cancer.
Purpose of the Study:
- To review the role of cytokines in cancer progression.
- To highlight the contribution of cytokines to cancer-related symptoms.
- To explore the potential of anti-cytokine therapies for symptom management.
Main Methods:
- Review of existing animal and human studies.
- Analysis of the link between cytokines and cancer symptoms.
- Examination of current research into anti-cytokine treatments.
Main Results:
- Cytokines promote tumor growth and spread.
- Cytokines contribute to asthenia, pain, cognitive dysfunction, anorexia, cachexia, fever, and metabolic issues in advanced cancer.
- Development of anti-cytokine treatments is underway.
Conclusions:
- Cytokines are key drivers of cancer progression and associated symptoms.
- Targeting cytokines offers a promising avenue for managing difficult-to-control symptoms in advanced cancer.
- Anti-cytokine therapies represent a potential new treatment modality.
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