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Racial differences in tamoxifen metabolism.

Flaws1, Lim, Luo

  • 1Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA

Annals of Epidemiology
|October 6, 2000
PubMed
Summary

Black women metabolize tamoxifen differently than white women, leading to higher levels of a less effective metabolite (N-desmethyltamoxifen). This may explain racial disparities in tamoxifen treatment outcomes for breast cancer patients.

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