Related Experiment Video
Updated: Aug 1, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
Published on: June 4, 2012
Musculoskeletal manifestations of bacterial endocarditis
1Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Context:
The incidence of staphylococcal infection has been increasing during the last 20 years.
Objective:
Report a case of staphylococcal endocarditis preceded by musculoskeletal manifestations, which is a rare form of clinical presentation.
Design:
Case report.
Case Report:
A 45-year-old-man, without addictions and without known previous cardiopathy, was diagnosed as having definitive acute bacterial endocarditis due to Staphylococcus aureus. Its etiology was community-acquired, arising from a non-apparent primary focus. In addition, the musculoskeletal symptoms preceded the infective endocarditis (IE) by about 1 month, which occurred together with other symptoms, e.g. mycotic aneurysms and petechiae. Later, the patient showed perforation of the mitral valve and moderate mitral insufficiency with clinical control.
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