Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Polychromatic phototest as a prognostic tool for polymorphic light eruption.

D Leroy1, A Dompmartin, K Faguer

  • 1Service de Dermatologie, Centre Hospitalier Universitaire, Caen, France. moulin-n@chu-caen.fr

Photodermatology, Photoimmunology & Photomedicine
|October 6, 2000
PubMed
Summary

Repetitive phototests can predict the course of polymorphic light eruption (PLE). Negative phototests indicate a benign form of PLE that may remit, while positive tests suggest a more chronic condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evolution of the sentinel lymph node procedure following the approval of adjuvant anti-PD-1 therapy for stage IIB and IIC melanoma: A multicenter study from RICMEL database.

Annales de dermatologie et de venereologie·2026
Same author

Atypical eosinophilic pustular folliculitis successfully treated with mepolizumab.

Annales de dermatologie et de venereologie·2025
Same author

Theragnostic approach of venous malformations in 2025: Similarities and differences with oncology advances.

Presse medicale (Paris, France : 1983)·2025
Same author

Hyperglycemic hyperosmolar coma induced by alpelisib in PIK3CA-related overgrowth spectrum (PROS).

Annales de dermatologie et de venereologie·2025
Same author

Efficacy, tolerance and acceptability of pulsed dye laser on facial and neckline telangiectasias in systemic scleroderma: a prospective open-label monocentric study in 21 patients.

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology·2024
Same author

Idiopathic facial aseptic granuloma in children: Management and long-term follow-up.

Annales de dermatologie et de venereologie·2023

Area of Science:

  • Dermatology
  • Photobiology
  • Immunodermatology

Background:

  • Polymorphic light eruption (PLE) diagnosis relies on history, lesion morphology, and phototesting.
  • Phototesting can be negative in up to 20% of PLE patients.
  • Understanding phototest results' link to disease evolution is crucial, as 24% of PLE patients achieve remission.

Purpose of the Study:

  • To investigate the link between phototest results and the clinical course of polymorphic light eruption (PLE).
  • To determine if repetitive phototests can serve as a prognostic marker for PLE.

Main Methods:

  • Recruited 40 patients diagnosed with PLE.
  • Performed one to three repetitive phototests per patient at various disease stages, including remission.
  • Ensured phototest reproducibility across different disease phases.

Related Experiment Videos

Main Results:

  • Phototests demonstrated good reproducibility, remaining consistently positive or negative for each patient.
  • Identified two subgroups: 30 active PLE patients and 10 in remission.
  • Positive phototests were exclusively observed in active PLE cases; all patients in remission had negative tests.

Conclusions:

  • Repetitive phototests show potential as a prognostic indicator for PLE.
  • Identified two PLE subtypes: a benign form (negative phototests, tendency to remit) and a chronic/severe form (positive phototests).