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Recurrence of rapidly progressive glomerulonephritis probably associated with two different kinds of drugs
S Aoki1, N Kotooka, M Yokoyama
1Department of Internal Medicine, Saga Medical School, Japan.
Clinical Nephrology
|October 6, 2000
Abstract:
We describe a rare case that developed a rapidly progressive glomerulonephritis twice in a 69-year-old man during a course of treatment, first with allopurinol and then with piperacillin. The cessation of each treatment was followed by spontaneous recovery in renal function. A renal biopsy showed crescentic glomerulonephritis with mild tubulointerstitial change and a skin biopsy showed leukocytoclastic vasculitis. This is, to our knowledge, a very rare case of crescentic glomerulonephritis, probably associated with vasculitis during a course of treatment with two different kinds of drugs.