Related Experiment Videos
Effect of risperidone on prolactinoma growth in a psychotic woman
1Department of Psychiatry, Mt. Sinai Hospital, Chicago, IL, USA.
Objective:
The case of a psychotic woman is described in which risperidone use was found to correspond with an increase in the size of a prolactinoma and prevented the return of serum prolactin level to baseline.
Methods:
Although the patient had been treated with a high dose of bromocriptine, her prolactin level remained elevated, causing persistent galactorrhea. The patient later was treated with olanzapine and carbamazepine successfully.
Results:
This case report highlights the role of risperidone on prolactin and discusses alternative methods of treating psychosis when the etiology is unclear, especially in younger patients.
Conclusions:
The authors recommend that additional studies regarding the relationship between the growth of prolactinoma and atypical antipsychotics would be worthwhile.