[The efficacy of acyclovir treatment in the therapy of herpetic keratitis]

There were investigated 51 patients, 19 female and 32 male, with ages between 12 and 80 years, hospitalized in the Dept. Ophthalm. of the City Hospital of Arad, during 1995-1997. From these, 21 had the clinical diagnosis of superficial keratitis, typical form of dendritic ulcer, 7 had non-typical forms, and 4 had stromal keratitis; 19 patients recurred. The diagnosis of herpetic keratitis was established correlating the clinical aspect with the cytologic examination, made on conjunctivo-corneane smears. A number of 32 patients received a specific treatment with Acyclovir, in an ointment form in local applications and on general route orally; there were also associated mydriatics and epitelizants of the cornea. The evolution of the disease was evaluated by comparing results obtained in different groups of patients.