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Updated: Oct 11, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Effects of low-density lipoproteins on blood coagulation and fibrinolytic activity
O A Azizova1, E V Roitman, I I Dement'eva
1Laboratory of Biophysical Basis of Pathology, Institute of Physicochemical Medicine, Russian Ministry of Health.
Abstract:
In vitro experiments showed that copper-oxidized low-density lipoproteins activate factors of the prothrombin complex in the whole blood and inhibit fibrin generation in both blood and plasma. Moreover, oxidized low-density lipoproteins inhibit fibrinolysis and impair the structure of fibrin clot, which results in hypercoagulation.
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