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Lactic acidosis associated with nucleoside reverse transcriptase inhibitors.

P M Caffrey1

  • 1Nicholas A. Rango Health Care Facility, New York, NY, USA.

The Journal of the Association of Nurses in AIDS Care : JANAC
|October 7, 2000
PubMed
Summary
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Nurses play a critical role in recognizing and managing lactic acidosis, a rare but serious side effect of nucleoside reverse transcriptase inhibitors used in HIV/AIDS treatment.

Area of Science:

  • Medical Science
  • Pharmacology
  • Nursing

Background:

  • Antiretroviral therapies (ART) for HIV/AIDS can be limited by drug resistance and adverse events.
  • Lactic acidosis is a rare but serious adverse event associated with nucleoside reverse transcriptase inhibitors (NRTIs).

Observation:

  • The recognition and management of lactic acidosis are crucial for patient outcomes.
  • Nursing assessment is vital for the early detection of lactic acidosis in patients with HIV/AIDS.

Findings:

  • This article reviews the clinical presentation, diagnosis, and treatment of lactic acidosis.
  • It also details essential nursing management strategies for patients with HIV/AIDS experiencing lactic acidosis.

Implications:

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  • Effective nursing interventions can improve the management of lactic acidosis in HIV/AIDS patients.
  • Understanding lactic acidosis is essential for optimizing antiretroviral therapy and patient care.