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Catalase activity in human erythrocytes: effect of phenoxyherbicides and their metabolites
B Bukowska1, A Chajdys, W Duda
1Department of Biophysics and Environmental Pollution, University of Lódz, Banacha 12/16, Lódz, 90-237, Poland. bukow@biol.uni.lodz.pl
Cell Biology International
|October 12, 2000
Abstract:
The effects of exposure to different concentrations of phenoxyherbicides and their metabolites were studied in human erythrocytes, with particular attention to catalase (CAT-EC. 1.11.1. 6- hydrogen peroxide: hydrogen peroxide oxidoreductase). 4-chloro-2-methylphenoxyacetic acid (MCPA), 2,4-dimethylphenol (2, 4-DMP) and 2,4-dichlorophenoxyacetic acid (2,4-D) did not affect CAT activity, but 2,4-dichlorophenol (2,4-DCP) and 2,4,5-trichlorophenol (2,4,5-TCP) decrease its activity, the latter being the more inhibitory.