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[Iron treatment by effervescent tablets (author's transl)].
Geburtshilfe Und Frauenheilkunde
|October 1, 1975
Summary
This study found that the effervescent iron tablet Loesferron effectively improved hemoglobin and red blood cell counts in postpartum patients. A single daily dose was sufficient and well-tolerated, suggesting a safe and effective iron supplement option.
Area of Science:
- Nutritional Science
- Hematology
- Pharmacology
Background:
- Postpartum iron deficiency anemia is a common complication affecting maternal health.
- Traditional iron supplements can cause gastrointestinal side effects, impacting patient compliance.
- Developing well-tolerated and effective iron therapies is crucial for postpartum recovery.
Purpose of the Study:
- To evaluate the efficacy and safety of a new effervescent iron tablet, Loesferron, in treating postpartum patients.
- To determine the optimal dosage for satisfactory therapeutic results.
- To assess the tolerability and potential side effects of the effervescent formulation.
Main Methods:
- A randomized, double-blind study was conducted.
- Fifty-seven postpartum patients were enrolled in the study.
- Treatment involved daily administration of the effervescent iron tablet Loesferron.
Main Results:
- Significant increases in hemoglobin (Hgb) and red blood cell count were observed.
- A daily dosage of one effervescent tablet proved sufficient for therapeutic success.
- No adverse side effects were reported, and the iron beverage was well-tolerated.
Conclusions:
- The effervescent iron tablet Loesferron is an effective treatment for postpartum anemia.
- A once-daily dose is adequate for achieving significant hematological improvements.
- The formulation's low incidence of side effects may be attributed to reduced local iron potentials in the gastric mucosa.