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Pneumonectomy for inflammatory lung disease.

D F Blyth1

  • 1Department of Cardio-thoracic Surgery, University of Natal Medical School, Durban, South Africa. blyth@wwh.und.ac.za

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|October 12, 2000
PubMed
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Pneumonectomy for inflammatory lung disease is safe and effective, with low mortality and morbidity. Adequate anti-tuberculosis drug coverage can improve outcomes for patients with tuberculosis.

Area of Science:

  • Thoracic Surgery
  • Pulmonary Medicine
  • Infectious Diseases

Background:

  • Pneumonectomy for inflammatory lung disease carries risks.
  • Assessing the risk/benefit ratio of pneumonectomy is crucial.

Purpose of the Study:

  • To evaluate the safety and efficacy of pneumonectomy for inflammatory lung disease.
  • To assess the risk/benefit ratio of the departmental policy on pneumonectomy.

Main Methods:

  • Retrospective analysis of patients undergoing pneumonectomy for inflammatory lung disease.
  • Inclusion of two 2-year periods (1991-1992 and 1996-1997).
  • Analysis of clinical indications, radiographic findings, morbidity, and mortality rates.

Main Results:

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  • 155 patients underwent pneumonectomy; 72% had a history of tuberculosis.
  • Mortality rate was 1.2% (2 patients); morbidity was 23%.
  • Post-pneumonectomy empyema occurred in 14.8% of patients, particularly those with pre-existing empyema.

    • Conclusions:

    • Pneumonectomy for inflammatory lung disease is a safe procedure with good outcomes.
    • Adequate pre-operative and operative anti-tuberculosis drug coverage may improve results in tuberculosis patients.
    • Pneumonectomy in children was uncomplicated; pneumonectomy in active tuberculosis had manageable risks.