Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modern prostate brachytherapy.

W M Butler1, G S Merrick, A T Dorsey

  • 1Schiffler Oncology Center, Wheeling Hospital, WV 26003-6300, USA. oncology@hgo.net

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
|October 12, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Argentum-Nitricum-Mental and Nervous Symptoms.

The Homoeopathic physician·2023
Same author

Treatment outcomes with permanent brachytherapy in high-risk prostate cancer patients stratified into prognostic categories.

Brachytherapy·2015
Same author

Chelative Addiction of Hydrazine to Coordinated Isocyanides. The Structure of 1,1'Dichloropallado-2,5-di(methylamino)-3,4-diazacyclopentadiene, [(CH3)2C2N4H4PdCl2)].

Inorganic chemistry·2014
Same author

Dielectrophoretic separation of prostate cancer cells.

Technology in cancer research & treatment·2012
Same author

Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy setting.

Prostate cancer and prostatic diseases·2009
Same author

Does hormonal manipulation in conjunction with permanent interstitial brachytherapy, with or without supplemental external beam irradiation, improve the biochemical outcome for men with intermediate or high-risk prostate cancer?

BJU international·2003
Same journal

Predictive dosimetric parameters for adaptive replanning in proton beam therapy for thoracic cancer.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

A case study of inhale and exhale split-course VMAT treatment to minimize dose to ribs.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Prospective clinical implementation of the robust optimization planning technique in long-course photon radiotherapy treatment for lung cancer.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Dosimetric comparison of target coverage, dose gradient, and low-dose bath in left-sided accelerated partial breast irradiation: CyberKnife versus conventional linac-based noncoplanar VMAT and 3D-CRT.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Cross-prescription validation of knowledge-based planning in prostate VMAT using a structured validation framework.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
Same journal

Dosimetric evaluation of beam block techniques in helical tomotherapy for extranodal nasal-type NK/T-cell lymphoma.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists·2026
See all related articles

Physicists use advanced tools to expand ultrasound prostate volumes into planning target volumes (PTVs) for treating extracapsular disease. This study reviews treatment designs, dosimetry timing, and quality parameters for improved prostate seed implant outcomes.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Prostate Cancer Treatment

Background:

  • Sophisticated computer-aided tools necessitate physicists converting ultrasound prostate volumes to planning target volumes (PTVs).
  • Established formalisms (AAPM TG 43) and calibration systems (NIST) facilitate changes in seed technology.
  • Lack of consensus in treatment design and evaluation leads to wide clinical practice variations.

Purpose of the Study:

  • To address the conversion of ultrasound prostate volumes to PTVs for extracapsular disease treatment.
  • To evaluate treatment design merits, including modified uniform seed-loading for homogeneous dose distribution.
  • To contrast timing of postoperative dosimetry and review quality parameters and their correlation with quality of life.

Main Methods:

Related Experiment Videos

  • Review of modified uniform seed-loading approaches for prostate implants.
  • Comparison of early versus delayed postoperative dosimetry.
  • Analysis of dosimetric parameters (D90, V100) and doses to critical structures (urethra, rectum, neurovascular bundles).

    • Main Results:

    • Modified uniform seed-loading may offer homogeneous dose distribution and low risk of overdosing critical structures.
    • Discussion on the trade-offs between optimal timing for dosimetry and clinical expediency.
    • Presentation of dose measures to organs at risk and their correlation with patient-reported outcomes.

    Conclusions:

    • Standardized approaches to PTV conversion and treatment evaluation are needed for consistent clinical practice.
    • Optimizing seed implant dosimetry timing and quality parameters can improve treatment efficacy and reduce toxicity.
    • Further research correlating dosimetric parameters with quality of life metrics is essential for refining prostate cancer radiotherapy.