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Improvement of exercise tolerance by single lead VDD pacemaker: evaluation using cardiopulmonary exercise test
1Second Department of Medicine, Yamanashi Medical University, Japan. hijiri@res.yamanashi-med.ac.jp
Pacing and Clinical Electrophysiology : PACE
|October 12, 2000
Summary
Single lead VDD pacing significantly improved exercise tolerance in patients with atrioventricular block. This pacing mode enhanced heart rate response and prolonged exercise duration, suggesting its utility for active individuals.
Area of Science:
- Cardiology
- Electrophysiology
- Exercise Physiology
Background:
- Atrioventricular block can impair cardiac function and exercise capacity.
- Single lead VDD pacing offers potential benefits for heart rate regulation.
Observation:
- Ten patients with atrioventricular block underwent cardiopulmonary testing.
- Exercise tests were performed comparing VDD pacing with VVI pacing.
Findings:
- VDD pacing demonstrated a significantly greater chronotropic response (maximal heart rate) compared to VVI pacing (106 vs 79 bpm, P=0.03).
- Exercise duration was prolonged (11.2 vs 10.5 min, P=0.01) and anaerobic threshold occurred at higher oxygen uptake (12.4 vs 10.0 mL/kg/min, P<0.01) with VDD pacing.
- Holter ECG confirmed reliable atrial sensing in VDD mode.
Implications:
- VDD pacing enhances exercise tolerance in patients with atrioventricular block.
- This pacing mode may be beneficial for individuals requiring physical activity.
- Further research can explore long-term outcomes and broader applications of VDD pacing.