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Related Concept Videos

Distinctive Features of Adult Stem Cells vs Cancer Stem Cells01:18

Distinctive Features of Adult Stem Cells vs Cancer Stem Cells

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A stem cell is an unspecialized cell that can divide without limit as needed and can, under specific conditions, differentiate into specialized cells.
Adult stem cells
Adult stem cells are tissue-specific; hence, they divide to develop the tissue from which they originate. One type of adult stem cell is the epithelial stem cell, which gives rise to the keratinocytes in the multiple layers of epithelial cells in the epidermis of the skin. Adult bone marrow has three distinct types of stem cells:...
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Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Embryonic Stem Cells00:58

Embryonic Stem Cells

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
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Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

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Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
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Stem Cell Niche01:26

Stem Cell Niche

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The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
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[Mesenchymal stem cells as potential source cartilage repair].

Orvosi hetilap·2005
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Self-renewal and differentiation of hematopoietic stem cells: a molecular approach (a review).

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[Impact of DNA chips on haematological oncology]

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[Restricted antibody diversity after bone marrow transplantation--homogeneous immunoglobulins].

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Related Experiment Video

Updated: Dec 19, 2025

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
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Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

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[A stem cell ... is stem cell?].

F Uher1

  • 1Országos Haematológiai és Immunológiai Intézet, Budapest.

Orvosi Hetilap
|October 12, 2000
PubMed
Summary

Neural stem cells from the brain can surprisingly regenerate blood tissues. These multipotent stem cells demonstrate broader developmental potential beyond the central nervous system, offering new repair possibilities.

Area of Science:

  • Neuroscience
  • Stem Cell Biology
  • Hematopoiesis

Context:

  • Adult central nervous system harbors neural stem cells capable of neurogenesis and gliogenesis.
  • These neural stem cells persist throughout life, suggesting potential roles in tissue repair.
  • Traditionally, stem cells are associated with renewable tissues like blood, gut, and skin.

Purpose:

  • To investigate the broader developmental potential of adult neural stem cells.
  • To explore the capacity of neural stem cells to generate non-neural cell types.
  • To assess the implications of neural stem cell plasticity for tissue regeneration.

Summary:

  • Neural stem cells, when transplanted into irradiated hosts, demonstrated the ability to generate diverse blood cell types, including myeloid, lymphoid, and early hematopoietic cells.

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Isolation and Culture of Adult Epithelial Stem Cells from Human Skin
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Isolating Stem Cells from Soft Musculoskeletal Tissues
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Isolating Stem Cells from Soft Musculoskeletal Tissues

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Related Experiment Videos

Last Updated: Dec 19, 2025

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
11:28

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Published on: May 11, 2016

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Isolation and Culture of Adult Epithelial Stem Cells from Human Skin
08:26

Isolation and Culture of Adult Epithelial Stem Cells from Human Skin

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Isolating Stem Cells from Soft Musculoskeletal Tissues
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  • This finding challenges the notion that stem cell potential is restricted to the tissue of origin.
  • Multipotential stem cells can maintain an undifferentiated state and adapt to environmental cues to differentiate into various cell lineages.

    • Impact:

    • The developmental plasticity of neural stem cells extends beyond the central nervous system, including blood regeneration.
    • This discovery opens new avenues for regenerative medicine and therapeutic strategies targeting CNS damage and hematological disorders.
    • Highlights the potential for stem cell therapies to address a wider range of conditions than previously understood.