Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Group B streptococcus in a general hospital.

B F Anthony, N F Concepcion

    The Journal of Infectious Diseases
    |November 1, 1975
    PubMed
    Summary

    Group B Streptococcus (GBS) is frequently identified in clinical settings, particularly in urine and genital samples. While sensitive to penicillin, GBS exhibits higher resistance to other antibiotics like tetracycline.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Level of maternal antibody required to protect neonates against early-onset disease caused by group B Streptococcus type Ia: a multicenter, seroepidemiology study.

    The Journal of infectious diseases·2001
    Same author

    Induction of group 17 specific antibodies by pneumococcal type 17F and 17A polysaccharide vaccines.

    Biologicals : journal of the International Association of Biological Standardization·2001
    Same author

    Pneumococcal type 22f polysaccharide absorption improves the specificity of a pneumococcal-polysaccharide enzyme-linked immunosorbent assay.

    Clinical and diagnostic laboratory immunology·2001
    Same author

    Genetic and immunologic characterization of a novel serotype 4, 15 strain of Neisseria meningitidis.

    FEMS immunology and medical microbiology·2000
    Same author

    Specificity of human antibodies reactive with pneumococcal C polysaccharide.

    Infection and immunity·2000
    Same author

    Estimation of group B streptococcus type III polysaccharide-specific antibody concentrations in human sera is antigen dependent.

    Infection and immunity·1998

    Area of Science:

    • Microbiology
    • Clinical Bacteriology
    • Infectious Diseases

    Background:

    • Beta-hemolytic streptococci are common pathogens.
    • Accurate identification and characterization of streptococcal groups are crucial for patient management.
    • Group B Streptococcus (GBS) can cause various infections, especially in neonates.

    Purpose of the Study:

    • To identify and characterize beta-hemolytic streptococci isolated from a general hospital.
    • To determine the prevalence and serotypes of Group B Streptococcus (GBS).
    • To assess the antimicrobial susceptibility patterns of GBS isolates.

    Main Methods:

    • Serological identification of beta-hemolytic streptococci.
    • Isolation and characterization of bacterial strains from various clinical samples.
    • Antimicrobial susceptibility testing using standard methods.

    Main Results:

    • Eighty-six percent of presumptive non-Group A and non-Group D beta-hemolytic streptococci were identified as GBS.
    • GBS were predominantly isolated from urine, female genital tract, and neonates.
    • Serotypes III and II were most common overall, with Ia, Ib, and Ic prevalent in respiratory samples. Type III caused most neonatal infections.
    • GBS showed in vitro sensitivity to penicillin G, ampicillin, and cephalothin, but high resistance to kanamycin and tetracycline.
    • Erythromycin, clindamycin, and chloramphenicol showed high efficacy against GBS, with minimal resistance.

    Conclusions:

    • Group B Streptococcus is a significant isolate in general hospital settings, often misidentified by presumptive tests.
    • Specific GBS serotypes are associated with particular infection sites and clinical outcomes, notably neonatal infections.
    • While GBS remains sensitive to penicillin, higher minimal inhibitory concentrations compared to Group A streptococci warrant consideration. Resistance to tetracycline is common, necessitating careful antibiotic selection.

    Related Experiment Videos