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Solid aneurysmal bone cyst in the humerus.

T Yamamoto1, T Marui, T Akisue

  • 1Department of Orthopaedic Surgery, Kobe University School of Medicine, Japan.

Skeletal Radiology
|October 12, 2000
PubMed
Summary
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This study details a rare solid variant of aneurysmal bone cyst in a patient's humerus, presenting as an osteolytic lesion with pathological fracture. Diagnosis was confirmed via imaging and histopathology, with no aneurysmal cavities found.

Area of Science:

  • Orthopedic Oncology
  • Skeletal Radiology
  • Bone Pathology

Background:

  • Solid variant of aneurysmal bone cyst (solid ABC) is a rare bone lesion.
  • This case presents a solid ABC in the left humerus with pathological fracture.

Observation:

  • Radiography showed a well-defined osteolytic lesion in the humerus diaphysis.
  • MRI revealed characteristic signal intensities on T1 and T2 weighted images, with diffuse enhancement post-contrast.
  • Histopathology confirmed a cellular proliferation without nuclear atypia, featuring osteoid formation and multinucleated giant cells, but lacking cystic spaces.

Findings:

  • The lesion was diagnosed as a solid ABC based on imaging and histopathological findings.
  • This case contributes to the literature on solid ABC, with only 22 prior cases reported in long bones.

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Implications:

  • Accurate diagnosis of solid ABC is crucial for appropriate management.
  • Understanding the imaging and pathological features aids in differentiating solid ABC from other bone lesions.
  • Further research into the etiology and behavior of solid ABC is warranted.