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Sonographic diagnosis of congenital tuberculosis: an experience with four cases
S B Grover1, D K Taneja, A Bhatia
1Department of Radiology and Imaging, Safdarjang Hospital, New Delhi 110029, India.
Insights
Congenital tuberculosis in infants presents with fever and enlarged liver/spleen. Ultrasound reveals characteristic lesions, enabling early diagnosis of this severe condition.
Area of Science:
- Pediatrics
- Infectious Diseases
- Radiology
Background:
- Congenital tuberculosis is a rare but severe condition.
- Early diagnosis is crucial for effective treatment and improved outcomes.
Observation:
- Four infants presented with pyrexia (fever) and hepatomegaly (enlarged liver).
- Abdominal sonography revealed multiple hypoechoeic (darker) foci in the liver and spleen.
Findings:
- Biopsies of these foci confirmed caseating granulomas with acid-fast bacilli, indicative of tuberculosis.
- Maternal endometrial tuberculosis and absence of tuberculosis in contacts supported the diagnosis of congenital tuberculosis.
Implications:
- This case highlights the importance of clinical suspicion in diagnosing congenital tuberculosis.
- Abdominal sonography is a valuable tool for early detection and antemortem diagnosis of this potentially fatal disease.
Abstract:
Abdominal sonography of four infants with pyrexia and hepatomegaly demonstrated multiple hypoechoeic hepatic and splenic foci, guided biopsies of which showed caseating granulomas with acid-fast bacilli. Evidence of tuberculosis in maternal endometrium and its exclusion in the contacts further confirmed a diagnosis of congenital tuberculosis. Clinical suspicion supplemented by careful sonography facilitated early detection and antemortem diagnosis of this potentially fatal disease.
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