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Injected periurethral collagen for postprostatectomy urinary incontinence: MR and CT appearance
D D Maki1, M P Banner, P Ramchandani
1Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Abdominal Imaging
|October 12, 2000
Summary
Imaging techniques like MRI and CT can identify periurethral collagen injections used to treat urinary incontinence after prostatectomy. These findings help distinguish the benign collagen from recurrent prostate cancer.
Area of Science:
- Radiology
- Urology
- Medical Imaging
Background:
- Urinary incontinence is a common complication following radical prostatectomy.
- Periurethral collagen injections are a treatment to improve urethral closure.
- Glutaraldehyde cross-linked bovine collagen is used for these injections.
Purpose of the Study:
- To describe the imaging appearance of periurethral collagen injections.
- To differentiate collagen deposits from recurrent prostate cancer on imaging.
Main Methods:
- Magnetic resonance imaging (MRI) and computed tomography (CT) were used.
- Collagen was studied in four male patients post-prostatectomy.
- In vitro scanning of collagen was performed for verification.
Main Results:
- Collagen deposits appeared as well-circumscribed nodules on MRI (T1 and T2 weighted).
- On contrast-enhanced CT, collagen presented as a hypoattenuating nodular-filling defect.
- Findings were observed in periurethral tissues and the penile bulb.
Conclusions:
- Specific imaging characteristics aid in identifying periurethral collagen.
- Differentiation from locally recurrent prostate carcinoma is possible.
- Avoids unnecessary work-up for benign findings.