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Measles eradication: is it in our future?

W A Orenstein¹, P M Strebel, M Papania

¹National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Ga. 30333, USA.

American Journal of Public Health

|October 13, 2000

Summary

Measles eradication is biologically feasible, offering a future free from millions of deaths and billions in costs. Despite challenges like political will and transmission dynamics, global measles elimination is achievable.

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Area of Science:

Public Health
Infectious Disease Epidemiology
Vaccinology

Background:

Measles currently causes approximately 1 million deaths annually.
Global measles control efforts face significant economic burdens related to treatment and prevention.

Purpose of the Study:

To evaluate the biological feasibility of global measles eradication.
To assess the criteria necessary for successful measles elimination.

Main Methods:

Analysis of four key criteria for eradication: human role in transmission, diagnostic accuracy, vaccine efficacy, and geographic elimination.
Review of successful measles transmission interruption in various regions.

Main Results:

Measles eradication is biologically feasible, supported by successful elimination in the Western Hemisphere and other regions.

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Identified impediments include political will, adult transmission, urbanization, HIV, waning immunity, and unsafe injections.

Conclusions:

Despite significant challenges, a strong case supports the pursuit of global measles eradication.
Measles eradication is considered an achievable future goal, contingent on addressing identified obstacles.