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Pramipexole is a possible effective treatment for primary orthostatic tremor (shaky leg syndrome)
1Department of Neurology, Cleveland Clinic Naples, 6101 Pine Ridge Rd, Naples, FL 34119, USA. finkelm@ccf.org.
Objective:
To report the successful treatment of primary orthostatic tremor in a 76-year-old man.
Background:
Primary orthostatic tremor is a rare condition, with few reports describing therapies. Established therapies had previously failed in our patient.
Methods:
Using an evidence-based evaluation of treatments via MEDLINE's GRATEFUL MED search engine, a therapeutic option was determined during the first consultation with the patient, and pramipexole therapy was initiated.
Results:
The therapy proved effective, and the patient had relief from his symptoms for the first time in 6 years.
Conclusion:
Pramipexole is a potential therapy for primary orthostatic tremor. Arch Neurol. 2000;57:1519-1520