Related Experiment Video
Updated: Jul 31, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
[Metabolic state of the other eye in post-traumatic uveitis]
Abstract:
Biochemical analysis of the paired eye lacrimal fluid lipid peroxides (diene conjugates, Schiff's bases, TBA-active products), antioxidant enzymes (catalase, superoxide dismutase), dehydrogenases (lactate and malate dehydrogenases), and lactic and pyruvic acids was carried out during the early and remote posttraumatic period in 468 patients after perforating injuries to the eye. Signs of activation of lipid peroxidation, antioxidants, dehydrogenases, and of glycolysis intensification were detected. These changes corresponded to the results of analysis of lacrimal fluid of the injured eye and depended on the severity of injury, time elapsed after it, and severity and course of posttraumatic uveitis. The author claims that the detected metabolic shifts in the lacrimal fluid of paired eye are involved in the pathogenesis of posttraumatic uveitis.
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