[Regularities of changes in parameters of humoral immunity in patients with eye diseases]

Changes in the levels of natural antibodies in the lacrimal fluid, saliva, and blood immunoglobulin concentrations were studied in patients with ocular injuries, inflammatory (keratitis, scleritis, uveitis) and noninflammatory diseases of the eyes. These values can be used as additional parameters for the diagnosis and prediction of the treatment efficiency. The immune system functions as a universal system with different compartments, and therefore mathematical relationships between these parameters were studied. Positive linear regression and correlation relationships were detected between -log2 antibody titers in the serum and lacrimal fluid, antibody titers in the saliva and serum, and negative relationships between antibody titers in the lacrimal fluid and IgA concentration and between lacrimal antibody titers and IgA level.