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Updated: Aug 22, 2026
Analyzing Murine Schwann Cell Development Along Growing Axons
Published on: November 21, 2012
Differential schwann cell migration in adult and old mice: an in vitro study
A R Santos1, M L Wada, F Langone
1Department of Cell Biology, State University of Campinas-UNICAMP, CP 6109, CEP 13089-970, SP, Campinas, Brazil.
Abstract:
The influence of aging on Schwann cell (SC) proliferation, migration and viability was studied in vitro. SCs were cultured in Ham F-10 medium enriched with 20% fetal calf serum (FCS), 40% FCS or collagen I gel plus 20% FCS. The migration of adult mice derived SCs was stimulated with FCS and collagen. With aging, SC migration, multiplication and viability decreased, indicating that ideal culturing conditions should be adjusted.
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