A Pediatric Case of Ophthalmoplegic Migraine with Recurrent Oculomotor Nerve Palsy

Ishikawa1, Yoshihara, Mizuki

  • 1Department of Ophthalmology, Nihon University School of Medicine, Nihon, Japan

Insights

Ophthalmoplegic migraine can cause recurrent oculomotor nerve palsy in children. Early diagnosis relies on detailed patient history, and topical timolol maleate may reduce migraine frequency and symptoms.

Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Ophthalmoplegic migraine is a rare condition characterized by recurrent cranial nerve palsies.
  • Oculomotor nerve palsy can present with symptoms like ptosis and double vision.

Purpose of the Study:

  • To report a case of ophthalmoplegic migraine in a young child presenting with recurrent oculomotor nerve palsy.
  • To highlight the importance of considering ophthalmoplegic migraine in the differential diagnosis of childhood oculomotor nerve palsy.

Main Methods:

  • A case study of a 4-year-old girl with recurrent ptosis and double vision.
  • Diagnostic workup included electroencephalography, computed tomography, single photon emission computed tomography, and cerebrovascular Doppler-ultrasound.
  • Treatment involved topical timolol maleate.

Main Results:

  • The patient experienced recurrent left oculomotor nerve palsy with internal ophthalmoplegia.
  • Neuroimaging and electroencephalography showed no significant abnormalities.
  • Topical timolol maleate significantly reduced the frequency and severity of migraine symptoms and oculomotor nerve palsy episodes.

Conclusions:

  • Ophthalmoplegic migraine should be considered in the diagnosis of isolated oculomotor nerve palsy in childhood.
  • A thorough patient history is crucial for diagnosing this condition.
  • Topical timolol maleate may be an effective treatment for managing symptoms.

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...