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[Osteoporosis in males].
M Audran1, E Legrand, D Chappard
1Service de Rhumatologie, CHU, 49033 Angers Cedex.
Annales De Medecine Interne
|October 18, 2000
Summary
Men have a lower incidence of osteoporotic fractures due to higher peak bone mass and longer life expectancy. Secondary causes like glucocorticoid therapy and ethanol abuse are common in younger men, with other factors contributing to bone loss and fracture risk.
Area of Science:
- Endocrinology
- Gerontology
- Orthopedics
Context:
- Osteoporotic fractures present differently in men compared to women.
- Understanding male osteoporosis is crucial for effective fracture prevention strategies.
Purpose:
- To elucidate the factors contributing to the lower incidence of osteoporotic fractures in men.
- To identify secondary causes and risk factors for osteoporosis in men, particularly younger individuals.
Summary:
- Men exhibit a lower incidence of osteoporotic fractures, attributed to higher peak bone mass, longer life expectancy, and the absence of menopause.
- In men, osteoporosis is frequently secondary, linked to prolonged glucocorticoid therapy, ethanol abuse, hypogonadism, and gastrointestinal disorders.
- Additional risk factors for bone loss include smoking, low calcium intake, vitamin D deficiency, hypercalciuria, and thyrotoxicosis, though their impact is debated.
- Increased fall propensity significantly contributes to fracture risk, especially in alcoholic men and elderly men with neurological conditions.
Impact:
- Provides insights into sex-based differences in osteoporosis and fracture risk.
- Highlights the importance of identifying secondary causes of osteoporosis in men.
- Informs clinical practice regarding risk assessment and management of male osteoporosis and fracture prevention.