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Updated: Aug 8, 2026

A Protocol for Genetic Induction and Visualization of Benign and Invasive Tumors in Cephalic Complexes of Drosophila melanogaster
Published on: September 11, 2013
[Oncovirus-induced permanent genetic instability in Drosophila melanogaster]
N V Mit'1, L B Dzhansugurova, R I Bersimbaev
1Department of Genetics and Molecular Biology, Al-Farabi State University Kazakhstan, Almaty.
Abstract:
Mutant alleles of a system of genetic instability induced by oncoviral DNAs were shown to demonstrate an unstable manifestation 500 generations after their emergence. A cytogenetic analysis of oncovirus-induced unstable lines has revealed numerous chromosome rearrangements. For the Lobe alleles of this system, a specific chromosome rearrangement, Df(2L) = 35C-36B, was found on the left arm of chromosome 2. We used recessive lethal mutations involving DNA rearrangements in a successful construction of cross systems for "explosive" instability.
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