Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anxiolytics for smoking cessation.

J R Hughes1, L F Stead, T Lancaster

  • 1Department of Psychiatry, University of Vermont, 38 Fletcher Place, Burlington, Vermont 05401-1419, USA. john.hughes@uvm.edu

The Cochrane Database of Systematic Reviews
|October 18, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Glioma: from genetic to cellular heterogeneity.

Frontiers in cell and developmental biology·2024
Same author

Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma.

Clinical and experimental immunology·2019
Same author

Complications following laryngeal sacculectomy in brachycephalic dogs.

The Journal of small animal practice·2017
Same author

Updated guidance for writing a British Association of Dermatologists clinical guideline: the adoption of the GRADE methodology 2016.

The British journal of dermatology·2017
Same author

Football Helmet Evaluation Based on Players' EEGs.

The Physician and sportsmedicine·2016
Same author

KvSNP: accurately predicting the effect of genetic variants in voltage-gated potassium channels.

Bioinformatics (Oxford, England)·2011
Same journal

Interventions to prevent or cease electronic cigarette use in children and adolescents.

The Cochrane database of systematic reviews·2026
Same journal

Drugs to improve anaemia, quality of life, and physical function in people with myelodysplastic syndromes (MDS).

The Cochrane database of systematic reviews·2026
Same journal

Interventions for smoking cessation in inpatient psychiatry settings.

The Cochrane database of systematic reviews·2026
Same journal

Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.

The Cochrane database of systematic reviews·2026
Same journal

Prognostic models for predicting intensive care unit admission or mortality in critically ill adults not yet been admitted to the intensive care unit.

The Cochrane database of systematic reviews·2026
Same journal

Views and experiences of weight management for people living with mobility‑limiting conditions, intellectual disabilities or severe mental illness: a qualitative evidence synthesis.

The Cochrane database of systematic reviews·2026
See all related articles

Anxiolytic drugs, used to treat anxiety, do not show consistent evidence for aiding long-term smoking cessation. However, current research does not definitively rule out a potential effect of these medications.

Area of Science:

  • Pharmacology
  • Addiction Medicine
  • Clinical Trials

Background:

  • Anxiety is a common symptom of nicotine withdrawal.
  • Smoking cessation may be influenced by neurotransmitter systems (dopamine, serotonin, norepinephrine) affected by anxiolytics.

Purpose of the Study:

  • To evaluate the efficacy of anxiolytic medications in achieving long-term smoking cessation.
  • To review randomized controlled trials of specific anxiolytics including buspirone, diazepam, and beta-blockers.

Main Methods:

  • Systematic review of randomized controlled trials from the Cochrane Tobacco Addiction Group trials register.
  • Inclusion criteria required at least six months of follow-up and comparison to placebo or alternative therapy.
  • Meta-analysis was performed where appropriate using a fixed effects model.

Related Experiment Videos

Main Results:

  • Limited trials (1-2) were available for individual anxiolytics like diazepam, meprobamate, and buspirone.
  • No drug demonstrated strong evidence for smoking cessation effectiveness.
  • Wide confidence intervals indicate that a potential effect cannot be excluded.

Conclusions:

  • Current evidence does not consistently support the use of anxiolytics for smoking cessation.
  • Further research is needed as a possible therapeutic effect remains plausible.