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Updated: Aug 1, 2026
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Neonatal bilirubin testing practices: reports from 312 laboratories enrolled in the Colege of American Pathologists
1Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA. dale.jane@mayo.edu
Objective:
To characterize laboratory practices for neonatal bilirubin testing and to identify opportunities for improvement.
Design:
A voluntary self-assessment questionnaire was used to assess the laboratory practices of 312 laboratories subscribing to the College of American Pathologists (CAP) Excel Chemistry Proficiency Testing Program.
Results:
A range of preanalytic and analytic practices were reported. The most notable problems identified were the use of overly long capillary puncture devices (17.8%), failure to protect the specimen from light prior to analysis (3.4%), failure to use a control containing >171 micromol/L bilirubin (26.1%), use of single-level control (4.2%), and lack of established linearity limits (7.0%).
Conclusion:
Opportunities exist to improve specimen collection, processing, and analysis for some physician-office and small-hospital laboratories.
