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Nucleotide sequence of the chromosomal ampC gene of Enterobacter aerogenes
K E Preston1, C C Radomski, R A Venezia
1Department of Pathology and Laboratory Medicine, Albany Medical Center Hospital, Albany, New York 12208, USA.
Abstract:
The AmpC beta-lactamase gene and a small portion of the regulatory ampR sequence of Enterobacter aerogenes 97B were cloned and sequenced. The beta-lactamase had an isoelectric point of 8 and conferred cephalosporin and cephamycin resistance on the host. The sequence of the cloned gene is most closely related to those of the ampC genes of E. cloacae and C. freundii.
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