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Filtration and infusion phlebitis: a double-blind prospective clinical study
American Journal of Hospital Pharmacy
|October 1, 1975
Summary
Using inline filters significantly reduced infusion phlebitis in postoperative patients. This method is recommended for routine intravenous therapy to improve patient outcomes and reduce complications.
Area of Science:
- Medical Science
- Clinical Nursing
- Infection Control
Background:
- Infusion phlebitis is a common complication of intravenous therapy.
- Identifying effective preventative measures is crucial for patient care.
Purpose of the Study:
- To investigate the impact of final inline filtration on the incidence of infusion phlebitis.
- To evaluate the efficacy of 0.45-mum membrane filters in reducing phlebitis.
Main Methods:
- Prospective, double-blind investigation.
- 146 postoperative patients were included.
- Comparison of filtered versus unfiltered intravenous fluids.
Main Results:
- Significantly reduced incidence of infusion phlebitis with 0.45-mum inline filters.
- Greatest reduction observed with unbuffered solutions and no set change over 72 hours.
- Filtered fluids prevented significant increases in white blood cell count and sedimentation rate.
Conclusions:
- Inline final filtration is an effective method for reducing infusion phlebitis.
- Routine use of inline filters is recommended for intravenous therapy.
- Filtration may mitigate inflammatory responses associated with intravenous fluids.