Pancreaticoduodenal preservation by hypothermic pulsatile perfusion for twenty-four hours

Pancreaticoduodenal grafts remained viable after transplantation only if a modified plasma perfusate with high osmolarity was used during the 24 hours of preservation. When regular plasma perfusate was used during the pancreaticoduodenal preservation, irreversible damage resulted, and all dogs died of ischemie or vascular changes in the first few days after transplantation.