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Active, multisite, laboratory-based surveillance for Cryptosporidium parvum

V Dietz1, D Vugia, R Nelson

  • 1Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.

Insights

Cryptosporidium parvum causes widespread illness, with 1,023 cases detected by active surveillance. This research provides crucial data on cryptosporidiosis burden in the United States.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • Cryptosporidium parvum outbreaks, like the 1993 Milwaukee incident, highlight its public health significance.
  • Transmission routes include contaminated water, food, animal contact, and childcare settings.
  • Accurate data on annual infection rates were previously unknown.

Purpose of the Study:

  • To establish active surveillance for Cryptosporidium parvum (C. parvum).
  • To determine the disease burden of cryptosporidiosis in the United States.
  • To provide initial data from the Foodborne Diseases Active Surveillance Network (FoodNet).

Main Methods:

  • Implemented active surveillance for C. parvum in 1997.
  • Integrated C. parvum surveillance into the FoodNet network.
  • Collected laboratory-confirmed cases from selected states.

Main Results:

  • Detected 1,023 laboratory-confirmed cases over the first 2 years of surveillance.
  • Calculated an annual incidence rate of 2.3 cases per 100,000 persons.
  • Observed a 16% hospitalization rate and a seasonal increase in cases among children.

Conclusions:

  • This study represents the first active, multistate ascertainment of cryptosporidiosis cases.
  • Provides valuable insights into the disease burden of C. parvum in the U.S.
  • Highlights the importance of ongoing surveillance for this pathogen.

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