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Phylogenetic relation of lungfish indicated by the amino acid sequence of myelin DM20
Y Tohyama1, T Ichimiya, H Kasama-Yoshida
1Institute of Life Science, Soka University, Hachioji, 192-8577, Tokyo, Japan.
Brain Research. Molecular Brain Research
|October 19, 2000
Abstract:
The cDNA of lungfish Protopterus annectens myelin DM20 was cloned, and the complete amino acid sequence of Protopterusannectens DM20 was deduced. When five possible phylogenetic trees were tested for the DM20 sequences, the maximum likelihood method supported tree 1 [((tetrapods, lungfish), coelacanth), zebrafish, shark] or tree 5 [(tetrapods, lungfish), (coelacanth, zebrafish), shark]. Both tree 1 and tree 5 indicate that lungfish is phylogenetically the closest to tetrapods among the living fishes.