Improved rapid method for electron microscopy of macro- and micro-tissue cultures
Related Experiment Video
Updated: Aug 18, 2026

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles
Published on: August 7, 2016
Abstract:
A rapid method of embedding macro- and micro-tissue cultures is described. The procedure involves use of a preshaped BEEM capsule for pelleting, fixation and embedding of tissue culture cells for electron microscopy. To obtain good contrast specimens prepared by this rapid method need a rather longer staining time with uranyl acetate than specimens prepared by standard methods. THis procedure takes only about 200 min from fixation and embedding to double staining with uranyl acetate and lead citrate. It should be useful for both monolayer tissue cultures and organ cultures in diagnostic and research studies on viral agents.
Related Concept Videos
Preparation of Samples for Electron Microscopy
Overview of Microscopy Techniques

