Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Orbital abscess masquerading as a rhabdomyosarcoma.

N Cota1, A Chandna, L J Abernethy

  • 1Department of Ophthalmology, Royal Liverpool University Hospital and the Department of Pediatric Ophthalmology, Alder Hey Children's Hospital, Liverpool, United Kingdom.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|October 21, 2000
PubMed
Summary

Orbital cellulitis is common, but rhabdomyosarcoma can mimic it. This case highlights the diagnostic challenge of distinguishing chronic orbital abscess from rhabdomyosarcoma in children.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Conjunctival lymphangioma as the initial manifestation of tuberous sclerosis complex in a child.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2025
Same author

Higher visual function deficits are independent of visual acuity measures in children with cerebral visual impairment.

Frontiers in human neuroscience·2024
Same author

Penile fracture associated with complete urethra and bilateral corpora cavernosa transection.

Annals of the Royal College of Surgeons of England·2021
Same author

Retroperitoneal paraganglioma: a chameleon masquerading as an adrenal pheochromocytoma.

Annals of the Royal College of Surgeons of England·2018
Same author

INSPiRE: an integrated approach to tackling household air pollution and improving health in rural Cambodia.

Public health·2017
Same author

Multifocal electroretinogram contributes to differentiation of various clinical pictures within a family with Bardet-Biedl syndrome.

Eye (London, England)·2014

Area of Science:

  • Ophthalmology
  • Pediatric Oncology
  • Infectious Diseases

Background:

  • Orbital cellulitis is a frequent cause of acute proptosis in children.
  • Rhabdomyosarcoma is a critical differential diagnosis in pediatric proptosis.
  • Differentiating orbital infections from tumors can be clinically challenging.

Observation:

  • A 6-year-old boy presented with acute nonaxial proptosis without systemic symptoms.
  • Initial differential diagnoses included orbital cellulitis, various orbital tumors, and abscess.
  • The patient exhibited minimal inflammatory signs, complicating the diagnosis.

Findings:

  • Orbital biopsy and microbiologic confirmation were essential for diagnosis.
  • A chronic orbital abscess was diagnosed, mimicking malignancy.

Related Experiment Videos

  • Clinical, laboratory, and imaging findings were insufficient for definitive diagnosis.

    • Implications:

    • This case underscores the difficulty in distinguishing chronic orbital infections from orbital rhabdomyosarcoma.
    • Clinicians must maintain a high index of suspicion for malignancy even with atypical presentations.
    • Accurate diagnosis requires a combination of clinical evaluation, imaging, and tissue sampling.