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Synthesis and Testing of Supported Pt-Cu Solid Solution Nanoparticle Catalysts for Propane Dehydrogenation
Published on: July 18, 2017
The catalytic center in nitrous oxide reductase, CuZ, is a copper-sulfide cluster
T Rasmussen1, B C Berks, J Sanders-Loehr
1Centre for Metalloprotein Spectroscopy and Biology, School of Chemical Sciences, and School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
Abstract:
The crystal structure of nitrous oxide reductase, the enzyme catalyzing the final step of bacterial denitrification in which nitrous oxide is reduced to dinitrogen, exhibits a novel catalytic site, called Cu(Z). This comprises a cluster of four copper ions bound by seven histidines and three other ligands modeled in the X-ray structure as OH(-) or H(2)O. However, elemental analyses and resonance Raman spectroscopy of isotopically labeled enzyme conclusively demonstrate that Cu(Z) has one acid-labile sulfur ligand. Thus, nitrous oxide reductase contains the first reported biological copper-sulfide cluster.
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