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Related Experiment Videos

Bone fluoride concentrations associated with fluoridated drinking water.

J Charen, D R Taves, J W Stamm

    Calcified Tissue International
    |April 17, 1979
    PubMed
    Summary
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    Recent studies suggested increased fluoride intake due to high bone fluoride values. However, reanalysis revealed errors in previous reports, and current bone fluoride levels in Rochester residents remain consistent with historical data, refuting claims of increased fluoride intake.

    Area of Science:

    • Environmental Health
    • Toxicology
    • Dental Public Health

    Background:

    • Recent Iowa bone fluoride data suggested a significant increase in fluoride intake.
    • This prompted reevaluation of fluoride exposure levels and their impact.

    Purpose of the Study:

    • To investigate the accuracy of recent high bone fluoride findings from Iowa.
    • To assess current bone fluoride levels in long-term residents of Rochester, NY, drinking fluoridated water.
    • To determine if there has been an increase in fluoride intake over time.

    Main Methods:

    • Reanalysis of Iowa bone specimens to verify reported fluoride levels.
    • Analysis of bone fluoride content in 17 long-term residents of Rochester, NY, with known water fluoride concentration (1 ppm F-).

    Related Experiment Videos

  • Comparison of new bone fluoride data with historical data (Zipkin et al., 1958).

    • Main Results:

    • Reanalysis of Iowa specimens indicated a reporting error, with actual fluoride levels being one-fourth of the initially reported values.
    • Bone fluoride values from Rochester residents (2085 +/- 270 ppm F- on an ashed-weight basis) were not significantly different from those predicted by 1958 data.
    • The findings do not support the hypothesis of increased fluoride intake.

    Conclusions:

    • The initial high bone fluoride values from Iowa were attributed to a laboratory reporting error.
    • Current bone fluoride levels in residents consuming 1 ppm F- water are consistent with historical levels.
    • There is no evidence to support a recent increase in fluoride intake based on these bone fluoride analyses.