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New developments in isotope labeling strategies for protein solution NMR spectroscopy
1Department of Biochemistry, University of Toronto, M5S 1A8, Toronto, Ontario, Canada.
Current Opinion in Structural Biology
|October 24, 2000
Abstract:
The development of novel isotope labeling strategies for proteins has facilitated the study of the structure and dynamics of these molecules. In addition, the recent emergence of alternative methods of bacterial expression for obtaining isotopically labeled proteins permits the study of new classes of important proteins by solution NMR methods.