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The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development

M R Brouns1, S F Matheson, K Q Hu

  • 1Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, MA 02129, USA.

Development (Cambridge, England)
|October 25, 2000
PubMed
Summary

P190 Rho GTPase activating protein (RhoGAP) is crucial for neural development, regulating actin rearrangements. Its absence causes severe defects in brain and neural tube formation, highlighting its role in cell adhesion and morphogenesis.

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