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Published on: January 27, 2010
Induction of labor by prostaglandin E(2) in relation to the Bishop score
1Department of Obstetrics and Gynecology, Technical University Hospital of Aachen, Aachen, Germany. birgit.kemp@post.rwth-aachen.de
Objective:
To compare the effectiveness of prostaglandin E(2) intravaginal gel with the intracervical gel in patients with an unfavorable cervix.
Method:
In a prospective multicenter trial 470 patients with unfavorable Bishop scores (3-4) were randomized to receive prostaglandin vaginal gel (2 mg) or intracervical gel (0.5 mg).
Results:
In patients with unfavorable Bishop scores the intravaginal application route resulted in a better cervical ripening, a shorter induction to delivery interval and a higher cumulative rate of deliveries during 24 h (P=0.01).
Conclusion:
Intravaginal instillation of prostaglandin E(2) gel for induction of labor is effective in patients with an unfavorable Bishop score of 3-4.
