[Renaissance of fluorides and calcium in the treatment of osteoporosis]

After the initial enthusiasm for fluorides in the treatment of osteoporosis there was a regression after some time and a "campaign" against fluorides. Recently in particular after the introduction of monofluorophosphate instead of NaF there is a revival of the use of fluorides in the treatment of osteoporosis, along with Ca, vitamin D and exercise as the classical combination of four. This can be supplemented by HRT in women, thyrocalcitonin, alendronate and other drugs with individual consideration of the optimal combination of these drugs. Also in future fluorides remain the foremost representative of the group of agents stimulating new formation of bone.