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What happens after conversion of treatment to continuous ambulatory peritoneal dialysis from hemodialysis?

S Sezer1, N Ozdemir, Z Arat

  • 1Department of Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey.

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis
|October 25, 2000
PubMed

Insights

Continuous ambulatory peritoneal dialysis (CAPD) shows better short-term outcomes than hemodialysis (HD) for patients with improved nutritional status, hypertension, and anemia control.

Area of Science:

  • Nephrology
  • Internal Medicine
  • Clinical Research

Background:

  • End-stage renal disease necessitates renal replacement therapy.
  • Hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) are common treatment modalities.
  • Patient outcomes can vary significantly between HD and CAPD.

Purpose of the Study:

  • To compare the clinical and laboratory outcomes of patients switching from HD to CAPD.
  • To evaluate the short-term efficacy of CAPD versus ongoing HD treatment.

Main Methods:

  • Prospective study following 34 patients after transitioning from HD to CAPD.
  • Data collection included clinical parameters, laboratory values (hemoglobin, ferritin, lipids, etc.), body composition, echocardiography, and medications.
  • Patients were followed for a mean of 19.8 months post-transition.

Main Results:

  • CAPD led to significant increases in hemoglobin, cholesterol, triglycerides, HDL, Lp(a), phosphorus, and iPTH.
  • Erythropoietin dosage and ferritin levels decreased.
  • Blood pressure, left ventricular hypertrophy, and cardiac dysfunction significantly improved.
  • Nutritional status (total protein, BMI, triceps skin fold) showed significant improvement.

Conclusions:

  • CAPD demonstrates superior short-term outcomes compared to HD.
  • CAPD offers better control of anemia and hypertension.
  • CAPD improves the nutritional status of patients with end-stage renal disease.

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