Heroin-induced spongiform leukoencephalopathy: value of diffusion MR imaging
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Updated: Sep 28, 2026

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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
Published on: December 9, 2010
1Department of Radiology, National Defense Medical Center and Tri-Service General Hospital, Taipei, Taiwan, Republic of China.
Journal of Computer Assisted Tomography
|October 25, 2000
Abstract:
The diffusion-weighted (DW) magnetic resonance (MR) imaging findings of a patient with subacute stage of heroin-induced vacuolating myelinopathy are reported. The diffuse decrease of apparent diffusion coefficient (ADC) of the white matter on DW imaging is attributed to restricted water diffusion, which is known to be caused by fluid entrapment within the myelin lamellae without demyelination.

