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Laparoscopic splenectomy in a patient with acquired angioneurotic edema
S Jabbour-Khoury1, G Khoury, A Soueide
1Department of Anesthesiology, American University of Beirut, Lebanon.
JSLS : Journal of the Society of Laparoendoscopic Surgeons
|October 29, 2000
Background:
We report the case of a 77-year-old female with acquired angioneurotic edema, C1 esterase inhibitor level = 4mg/dL, who was scheduled to undergo laparoscopic splenectomy.
Methods:
In the operating room, we administered on call 500 units (UI) of C1 esterase inhibitor concentrate intravenously. Intraoperative hemodynamic instability and generalized blood oozing improved following the administration of aprotinin 250000 UI intravenous (IV) drip.
Conclusion:
We recommend the administration of an antifibrinolytic agent in addition to C1 esterase inhibitor concentrate in patients with acquired angioneurotic edema.