Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Structure and function of the endoplasmic reticulum].

H U Schulze, H Staudinger

    Die Naturwissenschaften
    |July 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Conjunctivitis in dupilumab clinical trials.

    The British journal of dermatology·2019
    Same author

    Peak Pruritus Numerical Rating Scale: psychometric validation and responder definition for assessing itch in moderate-to-severe atopic dermatitis.

    The British journal of dermatology·2019
    Same author

    Macromolecular chemistry and biology.

    Schweizer Chemiker-Zeitung und Technik-Industrie·2010
    Same author

    A 12-week, placebo-controlled study of the efficacy and safety of ebastine, 10 and 20 mg once daily, in the treatment of perennial allergic rhinitis. Multicentre Study Group.

    Allergy·1999
    Same author

    Efficacy and safety of Azmacort MDI and Flovent Diskhaler.

    The Journal of allergy and clinical immunology·1998
    Same author

    End of New Zealand asthma epidemic.

    Lancet (London, England)·1995
    Same journal

    Could snort production reflect comfort in horses kept outdoors? A first study.

    Die Naturwissenschaften·2026
    Same journal

    Pyrazole-thiazolidine hybrids as α-amylase inhibitor: a mechanistic and computational investigation.

    Die Naturwissenschaften·2026
    Same journal

    Conventional methods may cause allometric analyses to be unreliable.

    Die Naturwissenschaften·2026
    Same journal

    Impact of habitat disturbance on activity pattern and diet of de brraza's monkey (Cercopithecus neglectus) in kafa biosphere reserve, South West Ethiopia.

    Die Naturwissenschaften·2026
    Same journal

    Ethnobotany of desert medicinal plants and their sustainable ethnomedicinal utilization.

    Die Naturwissenschaften·2026
    Same journal

    Temperature effects on survival and dormancy patterns across age groups in vulnerable land snail Vertigo moulinsiana.

    Die Naturwissenschaften·2026
    See all related articles

    Microsomal enzymes are uniformly distributed throughout the endoplasmic reticulum membrane system. Their catalytic activity relies on phospholipid and membrane structure for intracellular metabolite transport.

    Area of Science:

    • Biochemistry
    • Cell Biology
    • Molecular Biology

    Context:

    • Endoplasmic reticulum (ER) membrane architecture.
    • Distribution and function of microsomal enzymes.
    • Role of phospholipids in enzyme activity.

    Purpose:

    • To review the latest research on enzyme topology and ER molecular architecture.
    • To discuss the distribution and functional association of microsomal enzymes.
    • To elucidate the dependence of enzyme activity on membrane structure.

    Summary:

    • Microsomal enzymes are uniformly distributed across the endoplasmic reticulum (ER) membrane, not localized to specific regions.
    • Functionally related enzymes are found in close proximity to the ER membrane.
    • The catalytic activity of integral enzyme proteins is influenced by phospholipid composition and membrane structure.

    Related Experiment Videos

  • These membrane-bound complexes function as specific vectorial enzyme catalysts.
  • The ER plays a crucial role in the intracellular transport of metabolites.

    • Impact:

    • Provides insights into the organization and function of ER-bound enzymes.
    • Highlights the importance of membrane structure and phospholipids for enzyme catalysis.
    • Enhances understanding of the ER's role in metabolic pathways and intracellular transport.