Related Experiment Video
Updated: Jul 1, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
Published on: June 24, 2014
Antiphase oscillation of the left and right suprachiasmatic nuclei
H O de la Iglesia1, J Meyer, A Carpino
1Department of Neurology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA. hacho@bio.umass.edu
Abstract:
An unusual property of the circadian timekeeping systems of animals is rhythm "splitting," in which a single daily period of physical activity (usually measured as wheel running) dissociates into two stably coupled components about 12 hours apart; this behavior has been ascribed to a clock composed of two circadian oscillators cycling in antiphase. We analyzed gene expression in the hypothalamic circadian clock, the suprachiasmatic nucleus (SCN), of behaviorally "split" hamsters housed in constant light. The results show that the two oscillators underlying the split condition correspond to the left and right sides of the bilaterally paired SCN.
Related Concept Videos
Atomic Nuclei: Nuclear Spin
Atomic nuclei have a net nuclear spin, , which can have an integer or half-integer value. In atomic nuclei, the spins of protons are paired against each other but not with neutrons, and vice versa. Consequently, an even number of protons does not contribute to...
Atomic Nuclei: Magnetic Resonance
Atomic Nuclei: Nuclear Relaxation Processes
¹H NMR Signal Multiplicity: Splitting Patterns
Nuclear Overhauser Enhancement (NOE)
Atomic Nuclei: Types of Nuclear Relaxation
In spin–lattice or longitudinal relaxation, the excited spins exchange energy with the surrounding lattice as they return to the lower energy level. Among several mechanisms that contribute to spin–lattice relaxation, magnetic dipolar interactions are significant. Here, the excited nucleus transfers energy to a nearby...

