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Left ventricular diastolic dysfunction in lone atrial fibrillation determined by Doppler tissue imaging of mitral

M Thamilarasan1, R A Grimm, L L Rodriguez

  • 1Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195, USA.

The American Journal of Cardiology
|October 29, 2000
PubMed

Insights

This study found no atrial myopathy in lone atrial fibrillation patients. However, impaired diastolic function was detected, suggesting subtle heart muscle changes.

Area of Science:

  • Cardiology
  • Cardiac Electrophysiology
  • Echocardiography

Background:

  • Paroxysmal lone atrial fibrillation (LAF) affects many patients.
  • The underlying cardiac pathology in LAF remains incompletely understood.
  • Investigating potential myopathy in LAF is crucial for risk stratification.

Purpose of the Study:

  • To investigate for underlying atrial or ventricular myopathy in patients with paroxysmal LAF.
  • To assess cardiac function using standard echocardiography and Doppler tissue imaging.

Main Methods:

  • Utilized standard echocardiographic parameters.
  • Employed Doppler tissue imaging of mitral annular motion.
  • Analyzed data from patients diagnosed with paroxysmal lone atrial fibrillation.

Main Results:

  • No evidence of impaired atrial contractile function was observed.
  • Significant evidence of impaired diastolic function was identified in LAF patients.
  • Ventricular myopathy was not explicitly assessed but diastolic dysfunction suggests potential issues.

Conclusions:

  • Paroxysmal lone atrial fibrillation is not associated with overt atrial myopathy.
  • Impaired diastolic function is present in patients with paroxysmal LAF.
  • Further research into diastolic dysfunction mechanisms in LAF is warranted.

Keywords:
Non-programmatic

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