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Pathologic findings in late endophthalmitis after glaucoma filtering surgery.
A D Beck1, H E Grossniklaus, B Hubbard
1Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ophthalmology
|October 31, 2000
Summary
Late-onset endophthalmitis following glaucoma surgery, often caused by streptococci, can lead to severe inflammation and vision loss. Prompt diagnosis and treatment are crucial for managing this serious complication.
Area of Science:
- Ophthalmology
- Pathology
Background:
- Glaucoma filtering surgery, including trabeculectomy, is a common procedure to manage intraocular pressure.
- Late-onset endophthalmitis is a rare but severe complication that can occur months or years after glaucoma surgery.
Observation:
- This study reviewed four cases of enucleated eyes due to late-onset endophthalmitis after glaucoma filtering surgery.
- The interval between surgery and enucleation ranged from one to five years.
Findings:
- Streptococcal species were identified in all four cases.
- Histopathology revealed inflammation of the anterior segment, lens, and choroid, with one case showing granulomatous uveitis.
- Two patients had undergone trabeculectomy with adjunctive mitomycin-C.
Implications:
- Late-onset streptococcal endophthalmitis post-glaucoma surgery is aggressive and can result in poor outcomes.
- Phacoanaphylaxis and granulomatous uveitis may be contributing factors to the poor prognosis.