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Plastic microfluidic devices modified with polyelectrolyte multilayers

Barker1, Tarlov, Canavan

  • 1National Institute of Standards & Technology, Gaithersburg, Maryland 20899, USA. sbarker@nist.gov

Analytical Chemistry
|October 31, 2000
PubMed
Summary
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Polyelectrolyte multilayers (PEMs) were used to modify plastic microchannels, significantly improving surface chemistry control. This method standardizes electroosmotic flow (EOF) mobility across different plastic substrates like polystyrene and PETG.

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Microfluidics

Background:

  • Controlling polymer surface chemistry is vital for plastic microfluidic devices.
  • Variations in electroosmotic flow (EOF) mobility exist between different plastic substrates.
  • Surface modification is needed to standardize microchannel performance.

Purpose of the Study:

  • To use polyelectrolyte multilayers (PEMs) to alter and control the surface chemistry of plastic microchannels.
  • To achieve consistent EOF mobility across different polymer substrates.
  • To evaluate the efficacy and benefits of PEM surface modification.

Main Methods:

  • Fabricating microchannels in polystyrene (PS) and poly(ethylene terephthalate) glycol (PETG) plastics.
  • Coating microchannels with alternating layers of poly(allylamine hydrochloride) and poly(styrene sulfonate) (PEMs).

Related Experiment Videos

  • Evaluating surface modification using X-ray photoelectron spectroscopy (XPS) and measuring EOF mobility.

    • Main Results:

    • PEM modification resulted in highly similar electroosmotic mobilities for both PS and PETG microchannels.
    • XPS confirmed successful surface modification.
    • PEM-coated channels exhibited excellent wettability and reproducible results.

    Conclusions:

    • PEMs provide an effective method for controlling surface chemistry and standardizing EOF mobility in plastic microfluidic devices.
    • PEMs offer a robust, reproducible, and easily fabricated solution for microchannel surface modification.
    • The enhanced wettability and controlled flow characteristics of PEM-coated channels are beneficial for microfluidic applications.